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» Evolving genetic regulatory networks for systems biology
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BMCBI
2008
146views more  BMCBI 2008»
15 years 6 months ago
Rank-based edge reconstruction for scale-free genetic regulatory networks
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
Guanrao Chen, Peter Larsen, Eyad Almasri, Yang Dai
BERTINORO
2005
Springer
15 years 11 months ago
Evolving Fractal Gene Regulatory Networks for Graceful Degradation of Software
Fractal proteins are an evolvable method of mapping genotype to phenotype through a developmental process, where genes are expressed into proteins comprised of subsets of the Mande...
Peter J. Bentley
BIB
2008
93views more  BIB 2008»
15 years 6 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
ICANN
2007
Springer
16 years 7 days ago
Identifying Binding Sites in Sequential Genomic Data
The identification of cis-regulatory binding sites in DNA is a difficult problem in computational biology. To obtain a full understanding of the complex machinery embodied in genet...
Mark Robinson, Cristina González Castellano...
SAGA
2005
Springer
15 years 11 months ago
Self-replication, Evolvability and Asynchronicity in Stochastic Worlds
We consider temporal aspects of self-replication and evolvability – in particular, the massively asynchronous parallel and distributed nature of living systems. Formal views of s...
Chrystopher L. Nehaniv