4167 search results - page 511 / 834 » Evolutionary functional testing |
179
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BMCBI
2007
15 years 6 months ago
2007
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
163
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BMCBI
2008
15 years 6 months ago
2008
Background: The expansion of raw protein sequence databases in the post genomic era and availability of fresh annotated sequences for major localizations particularly motivated us...
203
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BMCBI
2008
15 years 6 months ago
2008
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
189
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BMCBI
2006
15 years 6 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
186
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GPEM
2008
15 years 6 months ago
2008
In this work a cooperative, bid-based, model for problem decomposition is proposed with application to discrete action domains such as classification. This represents a significan...