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» Evolutionary Computation for Modeling and Optimization
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BMCBI
2010
118views more  BMCBI 2010»
15 years 6 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
PPOPP
1995
ACM
15 years 10 months ago
A Model and Compilation Strategy for Out-of-Core Data Parallel Programs
It is widely acknowledged in high-performance computing circles that parallel input/output needs substantial improvement in order to make scalable computers truly usable. We prese...
Rajesh Bordawekar, Alok N. Choudhary, Ken Kennedy,...
JCNS
2010
104views more  JCNS 2010»
15 years 5 months ago
A new look at state-space models for neural data
State space methods have proven indispensable in neural data analysis. However, common methods for performing inference in state-space models with non-Gaussian observations rely o...
Liam Paninski, Yashar Ahmadian, Daniel Gil Ferreir...
BMCBI
2005
108views more  BMCBI 2005»
15 years 6 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMEI
2008
IEEE
16 years 1 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang