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BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
15 years 6 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
RANDOM
1998
Springer
15 years 11 months ago
Using Approximation Hardness to Achieve Dependable Computation
Abstract. Redundancy has been utilized to achieve fault tolerant computation and to achieve reliable communication in networks of processors. These techniques can only be extended ...
Mike Burmester, Yvo Desmedt, Yongge Wang
HPDC
2010
IEEE
15 years 7 months ago
Cloud computing paradigms for pleasingly parallel biomedical applications
Cloud computing offers new approaches for scientific computing that leverage the major commercial hardware and software investment in this area. Closely coupled applications are s...
Thilina Gunarathne, Tak-Lon Wu, Judy Qiu, Geoffrey...
BMCBI
2007
146views more  BMCBI 2007»
15 years 6 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
WWW
2005
ACM
16 years 7 months ago
On optimal service selection
While many works have been devoted to service matchmaking and modeling nonfunctional properties, the problem of matching service requests to offers in an optimal way has not yet b...
Piero A. Bonatti, P. Festa