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BMCBI
2008
135views more  BMCBI 2008»
15 years 7 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
BMCBI
2006
166views more  BMCBI 2006»
15 years 7 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
TEC
2002
161views more  TEC 2002»
15 years 7 months ago
A fast and elitist multiobjective genetic algorithm: NSGA-II
Multiobjective evolutionary algorithms (EAs) that use nondominated sorting and sharing have been criticized mainly for their: 1) ( 3) computational complexity (where is the number ...
Kalyanmoy Deb, Samir Agrawal, Amrit Pratap, T. Mey...
ECBS
2007
IEEE
97views Hardware» more  ECBS 2007»
16 years 1 months ago
A Service-Oriented Extension of the V-Modell XT
The ever growing size and complexity of both technical and business systems requires efficient software engineering approaches to keep development cost under control while still ...
Michael Meisinger, Ingolf Krüger
ICSE
1999
IEEE-ACM
15 years 11 months ago
Architectural Framework Modeling in Telecommunication Domain
Architectural frameworks have shown to increase the design reusability in large-scale object-oriented systems. Drawing on experience in complex software systems development in tel...
Giulio Fregonese, Alessandro Zorer, Giovanni Corte...