Background: The design of long oligonucleotides for spotted DNA microarrays requires detailed attention to ensure their optimal performance in the hybridization process. The main ...
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
Sungroh Yoon, Jessica C. Ebert, Eui-Young Chung, G...
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Background: Microarray time series studies are essential to understand the dynamics of molecular events. In order to limit the analysis to those genes that change expression over ...
Barbara Di Camillo, Gianna Toffolo, Sreekumaran K....