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195
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BMCBI
2010
15 years 6 months ago
2010
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
180
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BMCBI
2010
15 years 6 months ago
2010
Background: The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene sel...
196
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BMCBI
2010
15 years 6 months ago
2010
Background: To understand the evolutionary role of Lateral Gene Transfer (LGT), accurate methods are needed to identify transferred genes and infer their timing of acquisition. Ph...
161
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BMCBI
2010
15 years 6 months ago
2010
Background: Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introdu...
186
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BMCBI
2010
15 years 6 months ago
2010
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...