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BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
111views more  BMCBI 2010»
15 years 6 months ago
Comparative performances of DNA barcoding across insect orders
Background: Previous studies on insect DNA barcoding provide contradictory results and suggest not consistent performances across orders. This work aims at providing a general eva...
Massimiliano Virgilio, Thierry Backeljau, Bruno Ne...
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
LINNAEUS: A species name identification system for biomedical literature
Background: The task of recognizing and identifying species names in biomedical literature has recently been regarded as critical for a number of applications in text and data min...
Martin Gerner, Goran Nenadic, Casey M. Bergman
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BMCBI
2010
137views more  BMCBI 2010»
15 years 6 months ago
BS Seeker: precise mapping for bisulfite sequencing
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
Pao-Yang Chen, Shawn Cokus, Matteo Pellegrini
BMCBI
2010
136views more  BMCBI 2010»
15 years 6 months ago
An integrated Bayesian analysis of LOH and copy number data
Background: Cancer and other disorders are due to genomic lesions. SNP-microarrays are able to measure simultaneously both genotype and copy number (CN) at several Single Nucleoti...
Paola M. V. Rancoita, Marcus Hutter, Francesco Ber...
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