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BMCBI
2007
104views more  BMCBI 2007»
15 years 7 months ago
TISs-ST: a web server to evaluate polymorphic translation initiation sites and their reflections on the secretory targets
Background: The nucleotide sequence flanking the translation initiation codon (start codon context) affects the translational efficiency of eukaryotic mRNAs, and may indicate the ...
Renato Vicentini, Marcelo Menossi
BMCBI
2008
158views more  BMCBI 2008»
15 years 7 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
BMCBI
2006
121views more  BMCBI 2006»
15 years 6 months ago
Evaluation of sequence alignments and oligonucleotide probes with respect to three-dimensional structure of ribosomal RNA using
Background: Availability of high-resolution RNA crystal structures for the 30S and 50S ribosomal subunits and the subsequent validation of comparative secondary structure models h...
Yadhu Kumar, Ralf Westram, Peter Kipfer, Harald Me...
BMCBI
2006
114views more  BMCBI 2006»
15 years 6 months ago
Evaluation and comparison of mammalian subcellular localization prediction methods
Background: Determination of the subcellular location of a protein is essential to understanding its biochemical function. This information can provide insight into the function o...
Josefine Sprenger, J. Lynn Fink, Rohan D. Teasdale
BMCBI
2006
117views more  BMCBI 2006»
15 years 6 months ago
SigFlux: A novel network feature to evaluate the importance of proteins in signal transduction networks
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...
Wei Liu, Dong Li, Jiyang Zhang, Yunping Zhu, Fuchu...