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» Evaluation of clustering algorithms for gene expression data
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RECOMB
2004
Springer
16 years 7 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
BMCBI
2007
180views more  BMCBI 2007»
15 years 6 months ago
Using expression arrays for copy number detection: an example from E. coli
Background: The sequencing of many genomes and tiling arrays consisting of millions of DNA segments spanning entire genomes have made high-resolution copy number analysis possible...
Dmitriy Skvortsov, Diana Abdueva, Michael E. Stitz...
JAMIA
2011
94views more  JAMIA 2011»
14 years 9 months ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
BMCBI
2010
124views more  BMCBI 2010»
15 years 6 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
AUSDM
2008
Springer
225views Data Mining» more  AUSDM 2008»
15 years 8 months ago
Evaluation of Malware clustering based on its dynamic behaviour
Malware detection is an important problem today. New malware appears every day and in order to be able to detect it, it is important to recognize families of existing malware. Dat...
Ibai Gurrutxaga, Olatz Arbelaitz, Jesús M. ...