Abstract. Scientists’ ability to generate and collect massive-scale datasets is increasing. As a result, constraints in data analysis capability rather than limitations in the av...
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
We present FEMine, an automatic system for image-based gene expression analysis. We perform experiments on the largest publicly available collection of Drosophila ISH (in situ hyb...
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...