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» Evaluation of clustering algorithms for gene expression data
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BMCBI
2008
87views more  BMCBI 2008»
15 years 6 months ago
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data
Background: Microarray technology has become very popular for globally evaluating gene expression in biological samples. However, non-linear variation associated with the technolo...
Carl R. Pelz, Molly Kulesz-Martin, Grover Bagby, R...
BMCBI
2007
265views more  BMCBI 2007»
15 years 6 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2006
154views more  BMCBI 2006»
15 years 6 months ago
An improved procedure for gene selection from microarray experiments using false discovery rate criterion
Background: A large number of genes usually show differential expressions in a microarray experiment with two types of tissues, and the p-values of a proper statistical test are o...
James J. Yang, Mark C. K. Yang
BMCBI
2007
149views more  BMCBI 2007»
15 years 6 months ago
Robust imputation method for missing values in microarray data
Background: When analyzing microarray gene expression data, missing values are often encountered. Most multivariate statistical methods proposed for microarray data analysis canno...
Dankyu Yoon, Eun-Kyung Lee, Taesung Park
RECOMB
2010
Springer
16 years 1 months ago
Hierarchical Generative Biclustering for MicroRNA Expression Analysis
Clustering methods are a useful and common first step in gene expression studies, but the results may be hard to interpret. We bring in explicitly an indicator of which genes tie ...
José Caldas, Samuel Kaski