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BMCBI
2007
167views more  BMCBI 2007»
15 years 6 months ago
Applying negative rule mining to improve genome annotation
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...
Irena I. Artamonova, Goar Frishman, Dmitrij Frishm...
BMCBI
2007
62views more  BMCBI 2007»
15 years 6 months ago
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
Andy G. Lynch, David E. Neal, John D. Kelly, Glyn ...
BMCBI
2007
99views more  BMCBI 2007»
15 years 6 months ago
Orthogonal projections to latent structures as a strategy for microarray data normalization
Background: During generation of microarray data, various forms of systematic biases are frequently introduced which limits accuracy and precision of the results. In order to prop...
Max Bylesjö, Daniel Eriksson, Andreas Sjö...
BMCBI
2007
160views more  BMCBI 2007»
15 years 6 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
BMCBI
2007
128views more  BMCBI 2007»
15 years 6 months ago
Compression-based classification of biological sequences and structures via the Universal Similarity Metric: experimental assess
Background: Similarity of sequences is a key mathematical notion for Classification and Phylogenetic studies in Biology. It is currently primarily handled using alignments. Howeve...
Paolo Ferragina, Raffaele Giancarlo, Valentina Gre...
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