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BMCBI
2008
99views more  BMCBI 2008»
15 years 6 months ago
A new real-time PCR method to overcome significant quantitative inaccuracy due to slight amplification inhibition
Background: Real-time PCR analysis is a sensitive DNA quantification technique that has recently gained considerable attention in biotechnology, microbiology and molecular diagnos...
Michele Guescini, Davide Sisti, Marco B. L. Rocchi...
BMCBI
2008
125views more  BMCBI 2008»
15 years 6 months ago
XplorSeq: A software environment for integrated management and phylogenetic analysis of metagenomic sequence data
Background: Advances in automated DNA sequencing technology have accelerated the generation of metagenomic DNA sequences, especially environmental ribosomal RNA gene (rDNA) sequen...
Daniel N. Frank
BMCBI
2008
148views more  BMCBI 2008»
15 years 6 months ago
StAR: a simple tool for the statistical comparison of ROC curves
Background: As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A ...
Ismael A. Vergara, Tomás Norambuena, Evandr...
BMCBI
2008
193views more  BMCBI 2008»
15 years 6 months ago
Missing value imputation for microarray gene expression data using histone acetylation information
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Qian Xiang, Xianhua Dai, Yangyang Deng, Caisheng H...
BMCBI
2007
181views more  BMCBI 2007»
15 years 6 months ago
ASMPKS: an analysis system for modular polyketide synthases
Background: Polyketides are secondary metabolites of microorganisms with diverse biological activities, including pharmacological functions such as antibiotic, antitumor and agroc...
Hongseok Tae, Eun-Bae Kong, Kiejung Park
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