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ALMOB
2007
151views more  ALMOB 2007»
15 years 6 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
AUTOMATICA
2007
142views more  AUTOMATICA 2007»
15 years 6 months ago
Lyapunov-based switching control of nonlinear systems using high-gain observers
Abstract— We consider dynamic output feedback practical stabilization of uniformly observable nonlinear systems, based on high-gain observers with saturation. We assume that unce...
Leonid B. Freidovich, Hassan K. Khalil
BIOINFORMATICS
2007
123views more  BIOINFORMATICS 2007»
15 years 6 months ago
A comparative genome approach to marker ordering
Motivation: Genome maps are fundamental to the study of an organism and essential in the process of genome sequencing which in turn provides the ultimate map of the genome. The in...
Thomas Faraut, Simon de Givry, Patrick Chabrier, T...
BMCBI
2010
143views more  BMCBI 2010»
15 years 6 months ago
Shape based kinetic outlier detection in real-time PCR
Background: Real-time PCR has recently become the technique of choice for absolute and relative nucleic acid quantification. The gold standard quantification method in real-time P...
Davide Sisti, Michele Guescini, Marco B. L. Rocchi...
BMCBI
2010
154views more  BMCBI 2010»
15 years 6 months ago
Fine-tuning structural RNA alignments in the twilight zone
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
Andreas Bremges, Stefanie Schirmer, Robert Giegeri...
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