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BIOINFORMATICS
2012
13 years 8 months ago
SSuMMo: rapid analysis, comparison and visualization of microbial communities
Motivation: Next-generation sequencing methods are generating increasingly massive datasets, yet still do not fully capture genetic diversity in the richest environments. To under...
Alex L. B. Leach, James P. J. Chong, Kelly R. Rede...
RECOMB
2002
Springer
16 years 6 months ago
DNA sequence evolution with neighbor-dependent mutation
We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this c...
Peter F. Arndt, Christopher B. Burge, Terence Hwa
IMSCCS
2006
IEEE
16 years 14 days ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
BMCBI
2004
177views more  BMCBI 2004»
15 years 6 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
PAM
2012
Springer
14 years 2 months ago
A Sequence-Oriented Stream Warehouse Paradigm for Network Monitoring Applications
Network administrators are faced with the increasingly challenging task of monitoring their network’s health in real time, drawing upon diverse and voluminous measurement data fe...
Lukasz Golab, Theodore Johnson, Subhabrata Sen, Je...