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» Encodings of the Sequence Constraint
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BMCBI
2007
133views more  BMCBI 2007»
15 years 6 months ago
MATLIGN: a motif clustering, comparison and matching tool
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
Matti Kankainen, Ari Löytynoja
BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
BMCBI
2007
115views more  BMCBI 2007»
15 years 6 months ago
Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
NAR
2002
82views more  NAR 2002»
15 years 6 months ago
PALS db: Putative Alternative Splicing database
PALS db is a collection of Putative Alternative Splicing information from 19 936 human UniGene clusters and 16 615 mouse UniGene clusters. Alternative splicing (AS) sites were pre...
Y.-H. Huang, Y.-T. Chen, J.-J. Lai, S.-T. Yang, U....
FPL
2010
Springer
188views Hardware» more  FPL 2010»
15 years 4 months ago
SeqHive: A Reconfigurable Computer Cluster for Genome Re-sequencing
We demonstrate how Field Programmable Gate Arrays (FPGAs) may be used to address the computing challenges associated with assembling genome sequences from recent ultra-high-through...
Kristian Stevens, Henry Chen, Terry Filiba, Peter ...