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» Emergence of feedback in artificial gene regulatory networks
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EVOW
2007
Springer
16 years 7 days ago
Modeling the Shoot Apical Meristem in A. thaliana : Parameter Estimation for Spatial Pattern Formation
Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Tim Hohm, Eckart Zitzler
CEC
2008
IEEE
15 years 6 months ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
193
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BMCBI
2008
166views more  BMCBI 2008»
15 years 6 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf
IDA
2009
Springer
15 years 3 months ago
Estimating Hidden Influences in Metabolic and Gene Regulatory Networks
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
Florian Blöchl, Fabian J. Theis
GECCO
2005
Springer
178views Optimization» more  GECCO 2005»
15 years 11 months ago
A co-evolutionary hybrid algorithm for multi-objective optimization of gene regulatory network models
In this paper, the parameters of a genetic network for rice flowering time control have been estimated using a multiobjective genetic algorithm approach. We have modified the rece...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...