Understanding the self-regulatory mechanisms controlling the spatial and temporal structure of multicellular organisms represents one of the major challenges in molecular biology. ...
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
We address the applicability of blind source separation (BSS) methods for the estimation of hidden influences in biological dynamic systems such as metabolic or gene regulatory net...
In this paper, the parameters of a genetic network for rice flowering time control have been estimated using a multiobjective genetic algorithm approach. We have modified the rece...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...