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» Emergence of feedback in artificial gene regulatory networks
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JCB
2002
131views more  JCB 2002»
15 years 5 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
BIOSYSTEMS
2007
111views more  BIOSYSTEMS 2007»
15 years 6 months ago
A Markovian approach to the control of genetic regulatory networks
This paper presents an approach for controlling gene networks based on a Markov chain model, where the state of a gene network is represented as a probability distribution, while ...
Peter C. Y. Chen, Jeremy W. Chen
CMSB
2006
Springer
15 years 9 months ago
Randomization and Feedback Properties of Directed Graphs Inspired by Gene Networks
Having in mind the large-scale analysis of gene regulatory networks, we review a graph decimation algorithm, called "leaf-removal", which can be used to evaluate the feed...
M. Cosentino Lagomarsino, P. Jona, B. Bassetti
BMCBI
2007
186views more  BMCBI 2007»
15 years 6 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
CEC
2005
IEEE
15 years 11 months ago
Clustering-based approach to identify solutions for the inference of regulatory networks
Abstract- In this paper we address the problem of finding valid solutions for the problem of inferring gene regulatory networks. Different approaches to directly infer the depende...
Christian Spieth, Felix Streichert, Nora Speer, An...