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» Emergence of feedback in artificial gene regulatory networks
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CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
15 years 11 months ago
iSimBioSys: An "In Silico" Discrete Event Simulation Framework for Modeling Biological Systems
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
BMCBI
2006
169views more  BMCBI 2006»
15 years 6 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
ISMIS
2005
Springer
15 years 11 months ago
Towards Ad-Hoc Rule Semantics for Gene Expression Data
The notion of rules is very popular and appears in different flavors, for example as association rules in data mining or as functional (or multivalued) dependencies in databases. ...
Marie Agier, Jean-Marc Petit, Einoshin Suzuki
BMCBI
2011
15 years 1 months ago
Multivariate analysis of microarray data: differential expression and differential connection
Background: Typical analysis of microarray data ignores the correlation between gene expression values. In this paper we present a model for microarray data which specifically all...
Harri T. Kiiveri