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» Emergence of feedback in artificial gene regulatory networks
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HYBRID
2001
Springer
15 years 10 months ago
Hybrid Modeling and Simulation of Biomolecular Networks
Abstract. In a biological cell, cellular functions and the genetic regulatory apparatus are implemented and controlled by a network of chemical reactions in which regulatory protei...
Rajeev Alur, Calin Belta, Franjo Ivancic
CISIS
2010
IEEE
15 years 4 months ago
Modeling of Stress-induced Regulatory Cascades Involving Transcription Factor Dimers
Regulatory cascades consisting of stress-induced gene modules and their transcriptional regulators were recently identified and quantitatively modeled using Artificial Neural Netwo...
Maria Manioudaki, Panayiota Poirazi
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
15 years 6 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
CEC
2003
IEEE
15 years 11 months ago
Transcription and evolution of a virtual bacteria culture
Abstract- This paper describes implementation details and results from a simulated multi-agent bacteria ecosystem. Each bacterium is encoded on a DNA-like genome, specifying the ge...
Ricardo M. Hoar, Joanne K. Penner, Christian Jacob
BMCBI
2006
136views more  BMCBI 2006»
15 years 6 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara