Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
Blazej Bulka, Marie desJardins, Stephen J. Freelan...
We present a data structure for efficient axis-aligned orthogonal range search on a set of n lines in a bounded plane. The algorithm requires O(log n + k) time in the worst case t...
Background: Peptide Mass Fingerprinting (PMF) is a widely used mass spectrometry (MS) method of analysis of proteins and peptides. It relies on the comparison between experimental...
Witold E. Wolski, Maciej Lalowski, Peter Jungblut,...
Background: In proteomic analysis, MS/MS spectra acquired by mass spectrometer are assigned to peptides by database searching algorithms such as SEQUEST. The assignations of pepti...
Background: The Medium-chain Dehydrogenases/Reductases (MDR) form a protein superfamily whose size and complexity defeats traditional means of subclassification; it currently has ...