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» Efficient protein alignment algorithm for protein search
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BMCBI
2007
179views more  BMCBI 2007»
15 years 6 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
BMCBI
2006
159views more  BMCBI 2006»
15 years 6 months ago
EpiJen: a server for multistep T cell epitope prediction
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
Irini A. Doytchinova, Pingping Guan, Darren R. Flo...
RECOMB
2003
Springer
16 years 6 months ago
Designing seeds for similarity search in genomic DNA
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
Jeremy Buhler, Uri Keich, Yanni Sun
GCB
1997
Springer
77views Biometrics» more  GCB 1997»
15 years 10 months ago
Statistics of large scale sequence searching
Motivation: Database search programs such as FASTA, BLAST or a rigorous Smith–Waterman algorithm produce lists of database entries, which are assumed to be related to the query....
Rainer Spang, Martin Vingron
BMCBI
2004
115views more  BMCBI 2004»
15 years 6 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry