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» Efficient protein alignment algorithm for protein search
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EUROGP
2005
Springer
15 years 11 months ago
Evolving L-Systems to Capture Protein Structure Native Conformations
Abstract. A protein is a linear chain of amino acids that folds into a unique functional structure, called its native state. In this state, proteins show repeated substructures lik...
Gabi Escuela, Gabriela Ochoa, Natalio Krasnogor
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
A database of phylogenetically atypical genes in archaeal and bacterial genomes, identified using the DarkHorse algorithm
Background: The process of horizontal gene transfer (HGT) is believed to be widespread in Bacteria and Archaea, but little comparative data is available addressing its occurrence ...
Sheila Podell, Terry Gaasterland, Eric E. Allen
BMCBI
2007
133views more  BMCBI 2007»
15 years 6 months ago
Semantic integration to identify overlapping functional modules in protein interaction networks
Background: The systematic analysis of protein-protein interactions can enable a better understanding of cellular organization, processes and functions. Functional modules can be ...
Young-Rae Cho, Woochang Hwang, Murali Ramanathan, ...
BIOCOMP
2007
15 years 7 months ago
Aldose Reductase and Nitric Oxide Synthase Role in Diabetic Retinopathy: A Bioinformatics Study
- Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus. We investigated the role of several proteins that are likely to be involved in the d...
Hanuman Thota, Nageswara rao Kunjam, Suresh Babu C...
JCB
2007
106views more  JCB 2007»
15 years 6 months ago
Clustered Sequence Representation for Fast Homology Search
We present a novel approach to managing redundancy in sequence databanks such as GenBank. We store clusters of near-identical sequences as a representative union-sequence and a se...
Michael Cameron, Yaniv Bernstein, Hugh E. Williams