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» Efficient protein alignment algorithm for protein search
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BIBE
2010
IEEE
144views Bioinformatics» more  BIBE 2010»
15 years 7 months ago
Knowledge-Guided Docking of Flexible Ligands to SH2 Domain Proteins
Studies of interactions between protein domains and ligands are important in many aspects such as cellular signaling and regulation. In this work, we applied a three-stage knowledg...
Haiyun Lu, Shamima Banu Bte Sm Rashid, Hao Li, Wee...
APBC
2004
15 years 7 months ago
EMAGEN: An Efficient Approach to Multiple Whole Genome Alignment
Following advances in biotechnology, many new whole genome sequences are becoming available every year. A lot of useful information can be derived from the alignment and compariso...
Jitender S. Deogun, Jingyi Yang, Fangrui Ma
CEC
2007
IEEE
15 years 10 months ago
Prediction of protein interactions by combining genetic algorithm with SVM method
This paper proposes a novel hybrid GA/SVM method that can predict the interactions between proteins intermediated by the protein-domain relations. Firstly, we represented a protein...
Bing Wang, Lu-Sheng Ge, Wen-You Jia, Li Liu, Fu-Ch...
CEC
2009
IEEE
16 years 28 days ago
Evolutionary design of the energy function for protein structure prediction
— Automatic protein structure predictors use the notion of energy to guide the search towards good candidate structures. The energy functions used by the state-of-the-art predict...
Pawel Widera, Jonathan M. Garibaldi, Natalio Krasn...
ICDE
2007
IEEE
167views Database» more  ICDE 2007»
16 years 7 months ago
GString: A Novel Approach for Efficient Search in Graph Databases
Graphs are widely used for modeling complicated data, including chemical compounds, protein interactions, XML documents, and multimedia. Information retrieval against such data ca...
Haoliang Jiang, Haixun Wang, Philip S. Yu, Shuigen...