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» Efficient protein alignment algorithm for protein search
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ISMB
1996
15 years 7 months ago
The Megaprior Heuristic for Discovering Protein Sequence Patterns
Several computeralgorithms for discovering patterns in groups of protein sequences are in use that are basedon fitting the parametersof a statistical model to a group of related s...
Timothy L. Bailey, Michael Gribskov
TIT
2010
170views Education» more  TIT 2010»
15 years 27 days ago
Belief propagation estimation of protein and domain interactions using the sum-product algorithm
We present a novel framework to estimate protein-protein (PPI) and domain-domain (DDI) interactions based on a belief propagation estimation method that efficiently computes inter...
Faruck Morcos, Marcin Sikora, Mark S. Alber, Dale ...
BMCBI
2010
160views more  BMCBI 2010»
15 years 6 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BIOCOMP
2006
15 years 7 months ago
Learning Genetic and Gene Bayesian Networks with Hidden Variables: Bilayer Verification Algorithm
To improve the recovery of gene-gene and marker-gene (eQTL) interaction networks from microarray and genetic data, we propose a new procedure for learning Bayesian networks. This a...
Jason E. Aten
RIVF
2008
15 years 7 months ago
Speeding up subset seed algorithm for intensive protein sequence comparison
Abstract--Sequence similarity search is a common and repeated task in molecular biology. The rapid growth of genomic databases leads to the need of speeding up the treatment of thi...
Van Hoa Nguyen, Dominique Lavenier