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» Efficient protein alignment algorithm for protein search
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ICCAD
2008
IEEE
127views Hardware» more  ICCAD 2008»
16 years 2 months ago
Design and optimization of a digital microfluidic biochip for protein crystallization
Proteins crystallization is a commonly used technique for protein analysis and subsequent drug design. It predicts the three-dimensional arrangement of the constituent amino acids...
Tao Xu, Krishnendu Chakrabarty, Vamsee K. Pamula
BMCBI
2010
153views more  BMCBI 2010»
15 years 6 months ago
PPLook: an automated data mining tool for protein-protein interaction
Background: Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of inter...
Shao-Wu Zhang, Yao-Jun Li, Li Xia, Quan Pan
BMCBI
2008
130views more  BMCBI 2008»
15 years 6 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2008
176views more  BMCBI 2008»
15 years 6 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
WABI
2007
Springer
123views Bioinformatics» more  WABI 2007»
16 years 3 days ago
Inverse Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Eagu Kim, John D. Kececioglu