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BMCBI
2007
78views more  BMCBI 2007»
15 years 6 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
BMCBI
2007
96views more  BMCBI 2007»
15 years 6 months ago
Structure and function predictions of the Msa protein in Staphylococcus aureus
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
Vijayaraj Nagarajan, Mohamed O. Elasri
JAIR
2008
157views more  JAIR 2008»
15 years 6 months ago
Qualitative System Identification from Imperfect Data
Experience in the physical sciences suggests that the only realistic means of understanding complex systems is through the use of mathematical models. Typically, this has come to ...
George Macleod Coghill, Ashwin Srinivasan, Ross D....
BMCBI
2005
106views more  BMCBI 2005»
15 years 6 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
BMCBI
2005
161views more  BMCBI 2005»
15 years 6 months ago
Non-linear mapping for exploratory data analysis in functional genomics
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...
Francisco Azuaje, Haiying Wang, Alban Chesneau