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BMCBI
2007
197views more  BMCBI 2007»
15 years 6 months ago
Boolean networks using the chi-square test for inferring large-scale gene regulatory networks
Background: Boolean network (BN) modeling is a commonly used method for constructing gene regulatory networks from time series microarray data. However, its major drawback is that...
Haseong Kim, Jae K. Lee, Taesung Park
BMCBI
2008
95views more  BMCBI 2008»
15 years 6 months ago
Unsupervised reduction of random noise in complex data by a row-specific, sorted principal component-guided method
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
Joseph W. Foley, Fumiaki Katagiri
BMCBI
2008
201views more  BMCBI 2008»
15 years 6 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2008
124views more  BMCBI 2008»
15 years 6 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...
CORR
2010
Springer
153views Education» more  CORR 2010»
15 years 6 months ago
The Complexity of Causality and Responsibility for Query Answers and non-Answers
An answer to a query has a well-defined lineage expression (alternatively called how-provenance) that explains how the answer was derived. Recent work has also shown how to comput...
Alexandra Meliou, Wolfgang Gatterbauer, Katherine ...