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BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BMCBI
2006
167views more  BMCBI 2006»
15 years 6 months ago
GOurmet: A tool for quantitative comparison and visualization of gene expression profiles based on gene ontology (GO) distributi
Background: The ever-expanding population of gene expression profiles (EPs) from specified cells and tissues under a variety of experimental conditions is an important but difficu...
Jason M. Doherty, Lynn K. Carmichael, Jason C. Mil...
BMCBI
2004
158views more  BMCBI 2004»
15 years 6 months ago
A novel Mixture Model Method for identification of differentially expressed genes from DNA microarray data
Background: The main goal in analyzing microarray data is to determine the genes that are differentially expressed across two types of tissue samples or samples obtained under two...
Kayvan Najarian, Maryam Zaheri, Ali Ajdari Rad, Si...
SOUPS
2005
ACM
15 years 12 months ago
Johnny 2: a user test of key continuity management with S/MIME and Outlook Express
Secure email has struggled with signifcant obstacles to adoption, among them the low usability of encryption software and the cost and overhead of obtaining public key certificat...
Simson L. Garfinkel, Robert C. Miller
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 11 months ago
Latent Structure Models for the Analysis of Gene Expression Data
Cluster methods have been successfully applied in gene expression data analysis to address tumor classification. By grouping tissue samples into homogeneous subsets, more systema...
Dong Hua, Dechang Chen, Xiuzhen Cheng, Abdou Youss...