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BMCBI
2010
136views more  BMCBI 2010»
15 years 6 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2005
114views more  BMCBI 2005»
15 years 6 months ago
Extension of Lander-Waterman theory for sequencing filtered DNA libraries
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
Michael C. Wendl, W. Bradley Barbazuk
SC
2004
ACM
15 years 12 months ago
A Performance and Scalability Analysis of the BlueGene/L Architecture
This paper is structured as follows. Section 2 gives an architectural description of BlueGene/L. Section 3 analyzes the issue of “computational noise” – the effect that the o...
Kei Davis, Adolfy Hoisie, Greg Johnson, Darren J. ...
BMCBI
2007
162views more  BMCBI 2007»
15 years 6 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
RTSS
2006
IEEE
16 years 15 days ago
Tightening the Bounds on Feasible Preemption Points
Caches have become invaluable for higher-end architectures to hide, in part, the increasing gap between processor speed and memory access times. While the effect of caches on timi...
Harini Ramaprasad, Frank Mueller