Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Background: The degree to which conventional DNA sequencing techniques will be successful for highly repetitive genomes is unclear. Investigators are therefore considering various...
This paper is structured as follows. Section 2 gives an architectural description of BlueGene/L. Section 3 analyzes the issue of “computational noise” – the effect that the o...
Kei Davis, Adolfy Hoisie, Greg Johnson, Darren J. ...
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Caches have become invaluable for higher-end architectures to hide, in part, the increasing gap between processor speed and memory access times. While the effect of caches on timi...