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BMCBI
2010
104views more  BMCBI 2010»
15 years 6 months ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
BMCBI
2010
112views more  BMCBI 2010»
15 years 6 months ago
TabSQL: a MySQL tool to facilitate mapping user data to public databases
Background: With advances in high-throughput genomics and proteomics, it is challenging for biologists to deal with large data files and to map their data to annotations in public...
Xiaoqin Xia, Michael McClelland, Yipeng Wang
BMCBI
2010
99views more  BMCBI 2010»
15 years 6 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BMCBI
2010
156views more  BMCBI 2010»
15 years 6 months ago
Mathematical model for empirically optimizing large scale production of soluble protein domains
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
Eisuke Chikayama, Atsushi Kurotani, Takanori Tanak...
BMCBI
2007
154views more  BMCBI 2007»
15 years 6 months ago
Classification of heterogeneous microarray data by maximum entropy kernel
Background: There is a large amount of microarray data accumulating in public databases, providing various data waiting to be analyzed jointly. Powerful kernel-based methods are c...
Wataru Fujibuchi, Tsuyoshi Kato
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