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BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
IJMMS
2007
96views more  IJMMS 2007»
15 years 6 months ago
Communicating emotion through a haptic link: Design space and methodology
Communication of affect across a distance is not well supported by current technology, despite its importance to interpersonal interaction in modern lifestyles. Touch is a powerfu...
Jocelyn Smith, Karon E. MacLean
BMCBI
2005
118views more  BMCBI 2005»
15 years 6 months ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
JCB
2002
160views more  JCB 2002»
15 years 6 months ago
Inference from Clustering with Application to Gene-Expression Microarrays
There are many algorithms to cluster sample data points based on nearness or a similarity measure. Often the implication is that points in different clusters come from different u...
Edward R. Dougherty, Junior Barrera, Marcel Brun, ...
NAR
2011
267views Computer Vision» more  NAR 2011»
15 years 1 months ago
EcoCyc: a comprehensive database of Escherichia coli biology
EcoCyc (http://EcoCyc.org) is a comprehensive model organism database for Escherichia coli K-12 MG1655. From the scientific literature, EcoCyc captures the functions of individual...
Ingrid M. Keseler, Julio Collado-Vides, Alberto Sa...