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BMCBI
2007
94views more  BMCBI 2007»
15 years 6 months ago
A structural analysis of in vitro catalytic activities of hammerhead ribozymes
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...
Yu Shao, Susan Wu, Chi Yu Chan, Jessie R. Klapper,...
BMCBI
2007
102views more  BMCBI 2007»
15 years 6 months ago
Setting up a large set of protein-ligand PDB complexes for the development and validation of knowledge-based docking algorithms
Background: The number of algorithms available to predict ligand-protein interactions is large and ever-increasing. The number of test cases used to validate these methods is usua...
Luis A. Diago, Persy Morell, Longendri Aguilera, E...
BMCBI
2011
14 years 9 months ago
Computable visually observed phenotype ontological framework for plants
Background: The ability to search for and precisely compare similar phenotypic appearances within and across species has vast potential in plant science and genetic research. The ...
Jaturon Harnsomburana, Jason M. Green, Adrian S. B...
ICDE
2003
IEEE
247views Database» more  ICDE 2003»
16 years 7 months ago
CLUSEQ: Efficient and Effective Sequence Clustering
Analyzing sequence data has become increasingly important recently in the area of biological sequences, text documents, web access logs, etc. In this paper, we investigate the pro...
Jiong Yang, Wei Wang 0010
KDD
2007
ACM
159views Data Mining» more  KDD 2007»
16 years 6 months ago
Constraint-driven clustering
Clustering methods can be either data-driven or need-driven. Data-driven methods intend to discover the true structure of the underlying data while need-driven methods aims at org...
Rong Ge, Martin Ester, Wen Jin, Ian Davidson