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BMCBI
2011
15 years 1 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
FOCS
2007
IEEE
16 years 27 days ago
On the Hardness and Smoothed Complexity of Quasi-Concave Minimization
In this paper, we resolve the smoothed and approximative complexity of low-rank quasi-concave minimization, providing both upper and lower bounds. As an upper bound, we provide th...
Jonathan A. Kelner, Evdokia Nikolova
ISCAS
2006
IEEE
122views Hardware» more  ISCAS 2006»
16 years 18 days ago
256-channel integrated neural interface and spatio-temporal signal processor
Abstract- We present an architecture and VLSI implemen- Various strategies in the analysis of spatio-temporal dynamtation of a distributed neural interface and spatio-temporal ics ...
J. N. Y. Aziz, Roman Genov, B. R. Bardakjian, M. D...
SIGMOD
2008
ACM
157views Database» more  SIGMOD 2008»
16 years 6 months ago
CRD: fast co-clustering on large datasets utilizing sampling-based matrix decomposition
The problem of simultaneously clustering columns and rows (coclustering) arises in important applications, such as text data mining, microarray analysis, and recommendation system...
Feng Pan, Xiang Zhang, Wei Wang 0010
BMCBI
2007
182views more  BMCBI 2007»
15 years 6 months ago
EDISA: extracting biclusters from multiple time-series of gene expression profiles
Background: Cells dynamically adapt their gene expression patterns in response to various stimuli. This response is orchestrated into a number of gene expression modules consistin...
Jochen Supper, Martin Strauch, Dierk Wanke, Klaus ...