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BMCBI
2010
108views more  BMCBI 2010»
15 years 1 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...
PLDI
2012
ACM
13 years 9 months ago
Diderot: a parallel DSL for image analysis and visualization
Research scientists and medical professionals use imaging technology, such as computed tomography (CT) and magnetic resonance imaging (MRI) to measure a wide variety of biological...
Charisee Chiw, Gordon Kindlmann, John Reppy, Lamon...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...
BMCBI
2008
135views more  BMCBI 2008»
15 years 6 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2008
160views more  BMCBI 2008»
15 years 6 months ago
Dynamic sensitivity analysis of biological systems
Background: A mathematical model to understand, predict, control, or even design a real biological system is a central theme in systems biology. A dynamic biological system is alw...
Wu Hsiung Wu, Feng Sheng Wang, Maw Shang Chang