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BIOCOMP
2008
15 years 8 months ago
Discoveries in shRNA Design
-- To successfully apply RNAi, the very first step is to design functional siRNA or shRNA sequences targeting specific genes. Many characteristics of functional synthetic siRNAs ha...
Hong Zhou, Xiao Zeng, Joseph Manthey
BMCBI
2007
89views more  BMCBI 2007»
15 years 6 months ago
Primique: automatic design of specific PCR primers for each sequence in a family
Background: In many contexts, researchers need specific primers for all sequences in a family such that each primer set amplifies only its target sequence and none of the others, ...
Jakob Fredslund, Mette Lange
BMCBI
2006
110views more  BMCBI 2006»
15 years 6 months ago
Design of a combinatorial DNA microarray for protein-DNA interaction studies
Background: Discovery of precise specificity of transcription factors is an important step on the way to understanding the complex mechanisms of gene regulation in eukaryotes. Rec...
Julian Mintseris, Michael B. Eisen
CHI
2009
ACM
16 years 7 months ago
Supporting carers in their caring role through design
Carers are people who look after family, partners or friends who could not manage without them because of frailness, illness or disability. Our contribution is to show the potenti...
Andrea Taylor, Richard Wilson, Stefan Agamanolis
CHI
2003
ACM
16 years 7 months ago
Ethnographic interviews guide design of ford vehicles website
This case study describes ethnographic interviews with vehicle buyers to learn how they make purchase decisions. The research was conducted for J. Walter Thompson (JWT), the digit...
Lori Anschuetz, Stephanie Rosenbaum