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» Development and the Baldwin Effect
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BMCBI
2006
111views more  BMCBI 2006»
15 years 6 months ago
Development of an unbiased statistical method for the analysis of unigenic evolution
Background: Unigenic evolution is a powerful genetic strategy involving random mutagenesis of a single gene product to delineate functionally important domains of a protein. This ...
Colleen D. Behrsin, Chris J. Brandl, David W. Litc...
BMCBI
2006
128views more  BMCBI 2006»
15 years 6 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2007
127views more  BMCBI 2007»
15 years 6 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...
BMCBI
2006
137views more  BMCBI 2006»
15 years 6 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
ISCA
2012
IEEE
191views Hardware» more  ISCA 2012»
13 years 9 months ago
VRSync: Characterizing and eliminating synchronization-induced voltage emergencies in many-core processors
Power consumption is a primary concern for microprocessor designers. Lowering the supply voltage of processors is one of the most effective techniques for improving their energy e...
Timothy N. Miller, Renji Thomas, Xiang Pan, Radu T...