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BMCBI
2010
160views more  BMCBI 2010»
15 years 7 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
113views more  BMCBI 2010»
15 years 7 months ago
Statistical method on nonrandom clustering with application to somatic mutations in cancer
Background: Human cancer is caused by the accumulation of tumor-specific mutations in oncogenes and tumor suppressors that confer a selective growth advantage to cells. As a conse...
Jingjing Ye, Adam Pavlícek, Elizabeth A. Lu...
CGF
2010
146views more  CGF 2010»
15 years 7 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
BRAIN
2010
Springer
15 years 6 months ago
Sparse Regression Models of Pain Perception
Discovering brain mechanisms underlying pain perception remains a challenging neuroscientific problem with important practical applications, such as developing better treatments f...
Irina Rish, Guillermo A. Cecchi, Marwan N. Baliki,...
TMI
2010
175views more  TMI 2010»
15 years 1 months ago
Spatially Adaptive Mixture Modeling for Analysis of fMRI Time Series
Within-subject analysis in fMRI essentially addresses two problems, the detection of brain regions eliciting evoked activity and the estimation of the underlying dynamics. In [1, 2...
Thomas Vincent, Laurent Risser, Philippe Ciuciu