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BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2006
144views more  BMCBI 2006»
15 years 6 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...
ICDE
2002
IEEE
130views Database» more  ICDE 2002»
16 years 7 months ago
Structural Joins: A Primitive for Efficient XML Query Pattern Matching
XML queries typically specify patterns of selection predicates on multiple elements that have some specified tree structured relationships. The primitive tree structured relations...
Shurug Al-Khalifa, H. V. Jagadish, Jignesh M. Pate...
CHI
2008
ACM
16 years 7 months ago
Pointing with fingers, hands and arms for wearable computing
Pointing is a fundamental enabling operation for human-computer interaction across a broad spectrum of scenarios. The paper presents a study exploring how to develop a pointing sy...
Ian Oakley, John Sunwoo, Ilyeon Cho
CHI
2005
ACM
16 years 6 months ago
Breaking the laws of action in the user interface
Fitts' law, Steering law and Law of crossing, collectively known as the laws of action, model the speed-accuracy tradeoffs in common HCI tasks. These laws impose a certain sp...
Per Ola Kristensson