11462 search results - page 2045 / 2293 » Developing Application-Centric Methods |
163
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BMCBI
2007
15 years 6 months ago
2007
Background: Cell specific gene expression is largely regulated by different combinations of transcription factors that bind cis-elements in the upstream promoter sequence. However...
168
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BMCBI
2010
15 years 6 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
171
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BMCBI
2010
15 years 6 months ago
2010
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: Finding over- or under-represented motifs in biological sequences is now a common task in genomics. Thanks to p-value calculation for motif counts, exceptional motifs ...
159
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BMCBI
2007
15 years 6 months ago
2007
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...