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BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
IJRR
2010
113views more  IJRR 2010»
15 years 4 months ago
On the Topology of Discrete Strategies
This paper explores a topological perspective of planning in the presence of uncertainty, focusing on tasks specified by goal states in discrete spaces. The paper introduces stra...
Michael Erdmann
DPPI
2003
ACM
15 years 11 months ago
Dancing with a machine: a case of experience-driven design
For experience-driven design to become an influential design strategy, much effort should be put into method development and elaborate case studies. In the present paper, we prese...
Paul Hekkert, Marc Mostert, Guido Stompff
WOSP
2010
ACM
16 years 1 months ago
Reducing performance non-determinism via cache-aware page allocation strategies
Performance non-determinism in computer systems complicates evaluation, use, and even development of these systems. In performance evaluation via benchmarking and simulation, nond...
Michal Hocko, Tomás Kalibera
MSWIM
2005
ACM
15 years 11 months ago
Content and service replication strategies in multi-hop wireless mesh networks
Emerging multi-hop wireless mesh networks have much different characteristics than the Internet. They have low dimensionality and large diameters. Content and service replication ...
Shudong Jin, Limin Wang