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HUC
2010
Springer
15 years 6 months ago
Augmenting on-screen instructions with micro-projected guides: when it works, and when it fails
We present a study that evaluates the effectiveness of augmenting on-screen instructions with micro-projection for manual task guidance unlike prior work, which replaced screen in...
Stephanie Rosenthal, Shaun K. Kane, Jacob O. Wobbr...
BMCBI
2010
167views more  BMCBI 2010»
15 years 6 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
An effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
BMCBI
2010
105views more  BMCBI 2010»
15 years 6 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
BMCBI
2008
133views more  BMCBI 2008»
15 years 6 months ago
SPIKE - a database, visualization and analysis tool of cellular signaling pathways
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
Ran Elkon, Rita Vesterman, Nira Amit, Igor Ulitsky...
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