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BMCBI
2010
120views more  BMCBI 2010»
15 years 6 months ago
Modeling expression quantitative trait loci in data combining ethnic populations
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
Ching-Lin Hsiao, Ie-Bin Lian, Ai-Ru Hsieh, Cathy S...
BMCBI
2010
92views more  BMCBI 2010»
15 years 6 months ago
YODA: Software to facilitate high-throughput analysis of chronological life span, growth rate, and survival in budding yeast
Background: The budding yeast Saccharomyces cerevisiae is one of the most widely studied model organisms in aging-related science. Although several genetic modifiers of yeast long...
Brady Olsen, Christopher J. Murakami, Matt Kaeberl...
BMCBI
2010
130views more  BMCBI 2010»
15 years 6 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BIOSYSTEMS
2008
77views more  BIOSYSTEMS 2008»
15 years 6 months ago
A computational model of chemotaxis-based cell aggregation
We present a computational model that successfully captures the cell behaviors that play important roles in 2-D cell aggregation. A virtual cell in our model is designed as an ind...
Manolya Eyiyurekli, Prakash Manley, Peter I. Lelke...
BMCBI
2008
153views more  BMCBI 2008»
15 years 6 months ago
Estimating the size of the solution space of metabolic networks
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Alfredo Braunstein, Roberto Mulet, Andrea Pagnani
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