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210
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BMCBI
2010
15 years 6 months ago
2010
Background: There is an increasing demand to assemble and align large-scale biological sequence data sets. The commonly used multiple sequence alignment programs are still limited...
176
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BMCBI
2010
15 years 6 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
150
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BMCBI
2007
15 years 6 months ago
2007
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
163
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BMCBI
2007
15 years 6 months ago
2007
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
187
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BMCBI
2007
15 years 6 months ago
2007
Background: The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This probl...