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287
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BMCBI
2008
15 years 6 months ago
2008
Background: While text-mining and distributed annotation systems both aim at capturing knowledge and presenting it in a standardized form, there have been few attempts to investig...
173
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BMCBI
2010
15 years 6 months ago
2010
Background: Illumina's second-generation sequencing platform is playing an increasingly prominent role in modern DNA and RNA sequencing efforts. However, rapid, simple, stand...
162
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BMCBI
2007
15 years 6 months ago
2007
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
197
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BMCBI
2008
15 years 6 months ago
2008
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
135
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BMCBI
2007
15 years 6 months ago
2007
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...