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BMCBI
2010
136views more  BMCBI 2010»
15 years 6 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2006
131views more  BMCBI 2006»
15 years 6 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
GIS
2008
ACM
16 years 7 months ago
GEDMWA: geospatial exploratory data mining web agent
An abundance of geospatial information is flourishing on the Internet but mining and disseminating these data is a daunting task. With anything published on the web available to t...
Edward Pultar, Martin Raubal, Michael F. Goodchild
CHI
2005
ACM
16 years 6 months ago
Comparing usability problems and redesign proposals as input to practical systems development
Usability problems predicted by evaluation techniques are useful input to systems development; it is uncertain whether redesign proposals aimed at alleviating those problems are l...
Erik Frøkjær, Kasper Hornbæk