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» Describing Semistructured Data
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BMCBI
2005
201views more  BMCBI 2005»
15 years 6 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
JCB
2000
103views more  JCB 2000»
15 years 6 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
BMCBI
2010
172views more  BMCBI 2010»
15 years 1 months ago
Nonparametric identification of regulatory interactions from spatial and temporal gene expression data
Background: The correlation between the expression levels of transcription factors and their target genes can be used to infer interactions within animal regulatory networks, but ...
Anil Aswani, Soile V. E. Keränen, James Brown...
TASE
2010
IEEE
15 years 1 months ago
Clear and Precise Specification of Ecological Data Management Processes and Dataset Provenance
Abstract--With the availability of powerful computational and communication systems, scientists now readily access large, complicated derived datasets and build on those results to...
Leon J. Osterweil, Lori A. Clarke, Aaron M. Elliso...
ASPLOS
2009
ACM
16 years 7 months ago
Producing wrong data without doing anything obviously wrong!
This paper presents a surprising result: changing a seemingly innocuous aspect of an experimental setup can cause a systems researcher to draw wrong conclusions from an experiment...
Todd Mytkowicz, Amer Diwan, Matthias Hauswirth, Pe...