Predicting how well applications may run on modern systems is becoming increasingly challenging. It is no longer sufficient to look at number of floating point operations and commu...
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
The popularity of batch-oriented cluster architectures like Hadoop is on the rise. These batch-based systems successfully achieve high degrees of scalability by carefully allocati...
We consider the following Tree-Constrained Bipartite Matching problem: Given two rooted trees T1 = (V1, E1), T2 = (V2, E2) and a weight function w : V1 × V2 → R+, find a maximu...
Stefan Canzar, Khaled M. Elbassioni, Gunnar W. Kla...