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BMCBI
2010
178views more  BMCBI 2010»
15 years 6 months ago
CNV Workshop: an integrated platform for high-throughput copy number variation discovery and clinical diagnostics
Background: Recent studies have shown that copy number variations (CNVs) are frequent in higher eukaryotes and associated with a substantial portion of inherited and acquired risk...
Xiaowu Gai, Juan C. Perin, Kevin Murphy, Ryan O'Ha...
BMCBI
2010
114views more  BMCBI 2010»
15 years 6 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2007
93views more  BMCBI 2007»
15 years 6 months ago
Representing default knowledge in biomedical ontologies: application to the integration of anatomy and phenotype ontologies
Background: Current efforts within the biomedical ontology community focus on achieving interoperability between various biomedical ontologies that cover a range of diverse domain...
Robert Hoehndorf, Frank Loebe, Janet Kelso, Heinri...
BMCBI
2008
138views more  BMCBI 2008»
15 years 6 months ago
SynechoNET: integrated protein-protein interaction database of a model cyanobacterium Synechocystis sp. PCC 6803
Background: Cyanobacteria are model organisms for studying photosynthesis, carbon and nitrogen assimilation, evolution of plant plastids, and adaptability to environmental stresse...
Woo-Yeon Kim, Sungsoo Kang, Byoung-Chul Kim, Jeehy...
BMCBI
2006
178views more  BMCBI 2006»
15 years 6 months ago
MannDB - A microbial database of automated protein sequence analyses and evidence integration for protein characterization
Background: MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the dev...
Carol L. Ecale Zhou, Marisa Lam, Jason Smith, Adam...